导师姓名：吴志猛
性别：男
人气指数：390

所属院校：江南大学
所属院系：
职称：教授，博士生导师
导师类型：
招生专业：
研究领域： 工作经历：2013.11起江南大大学生物工程学院教授，博士生导师2011.11-2013.... [展开]


研究领域： 工作经历：2013.11起江南大大学生物工程学院教授，博士生导师2011.11-2013.10新西兰皇家科学院工业研究所，研究员2008.07-2011.11美国韦恩州立大学化学系，博士后2005.12-2008.6美国BarbaraAnnKarmanosCancerInstitute，博士后研究员教育背景：2002.9-2005.7浙江大学化学系理学博士1999.9-2002.7延边大学化学系，硕士1995.9-1999.7安徽师范大学化学系，学士学术兼职：受邀作为ChemicalCommunications,Journaloforganicchemistry,JournalofCombinatorialchemistry,Organic&BiomolecularChemistry,EuropeanJournalofOrganicChemistry,CurrentOrganicSynthesis,EuropeanJournalofMedicinalChemistry,ChemistryLetter,Australianjournalofchemistry,Bioorganic&MedicinalChemistry,CarbohydrateResearch等期刊的审稿人主要研究内容、目标及进展多年来一直从事糖化学与药物化学交叉的研究工作，研究领域涉及抗病毒药物研发，复杂寡糖的全合成以及发展化学酶法合成糖肽和糖蛋白等。团队成员将致力于以糖化学为基础的创新糖类药物研究为主线，利用糖的化学性质和生物学功能，设计和合成单糖，寡糖，多糖，糖肽以及糖缀化合物；开展糖类药物先导化合物的合成方法学研究并研究其构效关系；重点研究糖类化合物在抗病毒（HBV，HCV，HIV），癌症疫苗以及抗生素等领域的应用和开发。研究队伍本课题组期待每一位对我们课题感兴趣的高年级本科生，硕博士生和博士后的加盟；有意者请与我（生工A307室）联系。或者电话联系：**代表性文章著作及专利1.Z.Wu,X.Guo,J.Gao,Z.Guo.SortaseA-mediatedchemoenzymaticsynthesisofcomplexglycosylphosphatidylinositol-anchoredproteinChem.Commun.,2013,49,11689.（IF：6.38）2.Z.Wu,X.Guo,G.Guo,Z.Guo.ChemoenzymaticSynthesisoftheHumanCD52andCD24AntigenAnaloguesOrg.Lett.,2013,15,5906.(IF:6.14)3.X.Guo,Z.Wu（并列第一）,Z.Guo.NewMethodforSite-SpecificModificationofLiposomeswithProteinsUsingSortaseA-MediatedTranspeptidationBioconjugateChem.,2012,23,650.(IF:4.58)4.Z.Wu,Z.Guo.Sortase-MediatedTranspeptidationforSite-SpecificModificationofPeptides,Glycopeptides,andProteins(ReviewArticle)J.Carbohydr.Chem.2012,31,485.Z.Wu,X.Guo,Z.Guo.SortaseA-catalyzedpeptidecyclizationforthesynthesisofmacrocyclicpeptidesandglycopeptidesChem.Commun.,2011,47,9218.（IF：5.504）6.Z.Wu,X.Guo,Z.Guo.ChemoenzymaticSynthesisofGlycosylphosphatidylinositol-AnchoredGlycopeptideChem.Comm.,2010,46,5773.(IF:5.504)7.Z.Wu,X.Guo,Q.Wang,B.M.Swarts,Z.Guo.SortaseA-CatalyzedTranspeptidationofGlycosylphosphatidylinositolDerivativesforChemoenzymaticSynthesisofGPI-AnchoredProteinsJ.Am.Chem.Soc.2010,132,1567.(IF:8.58)8.Z.Wu,J.C.Drach,M.N.Prichard,M.Yanachkova,I.Yanachkov,T.L.Bowlin,J.Zemlicka.L-ValineEsterofCyclopropavir–aNewAntiviralProdrugAntiviralChemistryandChemotherapy,2009,20,37.9.Z.Wu,S.Zhou,J.Zemlicka.StereoselectiveapproachtotheZ-isomersofmethylenecyclopropaneanaloguesofnucleosides:AnewsynthesisofanitiviralsynguanolNucleosides,Nucleotides&NucleicAcids,2009,28,165.10.Z.Wu,X.Huang.TheMn(OAc)3-mediatedOxidativeFreeRadicalReactionofAlleneswithMalonicAcidEster:ANovelandEfficientMethodfortheSynthesisofMethyl4-Oxoalk-2-enoatesorButenolides.Synthesis,2006,45.11.F.Sa,Z.Wu,X.Huang.Highlyregio-andstereoselectivesynthesisofbeta-phenyl-chalcogenylallylsulfonesbyhydrochalcogenationreactionof1,2-allenylsulfonesSyntheticCommunications,2006,36,2603.12.Z.Wu,R.Shen,L,Wu,X.Huang.ANovelandEfficientMethodstoSynthesisofβ-organoselenosubtitutedAllyllicSulfoxidesChinesechemicalLetters,2005,16,1333.13.Z.Wu,R.Shen,L.Ren,X.Huang.EfficientSynthesisofβ-OrganochalcogenylAllylSulfoxidesviaRegioselectivelyHydrochalcogenationReactionof1,2-AllenylSulfoxides.Synthesis,2005,217114.Z.Wu,X.Huang.RegioselectivelyHydrochalcogenationReactionof1,2-AllenylPhosphineOxides.ANovelSynthesisofβ-OrganochalcogenylAllylPhosphineOxides.Synlett,2005,52615.X.Huang,Z.Wu.Cis-CarbocuprationofAcetylenicphosphineOxidesandItsApplicationintheStereoselectiveSynthesisofPolysunstitutedVinylphosphineOxides.Synthesis,2004,244 [收起]




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