翻译原文：

A major worldwide breakthrough in gene therapy was signalled last night after injections into the brain were used for the first time to successfully treat a degenerative brain disease.

 In a pioneering study, researchers used the treatment to bring about significant improvements in the mobility of Parkinson's sufferers. They said it could also herald a breakthrough in the treatment of other neurological disorders, such as Alzheimer's or epilepsy.

The 12 patients involved in the study - a world-first human gene therapy trial for a brain disease - all reported a substantial reduction in their symptoms after having a human gene injected.

Within months, their ability to move had improved on average by 30 per cent. Some reported a 65 per cent improvement in their mobility. Nathan Klein, 59, the first to undergo the pioneering treatment told The Daily Telegraph last night that before the gene therapy, he had been "in a state that nobody could survive". He said: "The treatment saved my life."