导师姓名：张继
性别：男
人气指数：470

所属院校：东北农业大学
所属院系：生命科学学院
职称：副教授
导师类型：硕导
招生专业：微生物学


通讯方式 :
电子邮件：lumenzi@163.com


科研工作 :
国家自然科学基金面上项目，大豆疫霉苏氨酰tRNA合成酶结构与Borrelidin结合位点解析国家自然科学基金青年项目，含氯化酶基因放线菌的筛选和农用新活性化合物的研究国家基础科学人才培养基金子项目，基于PCR技术的杂合型类异戊二烯次级代谢物的发现及生物合成的研究黑龙江省自然科学基金面上项目，松嫩平原盐碱地稀有放线菌及其活性代谢产物的挖掘黑龙江普通高等学校“青年学术骨干”支持计划项目，松嫩平原盐碱地中可培养耐（嗜）盐放线菌的多样性及其农用活性代谢产物的研究中国博士后基金，基于卤化酶基因为探针的基因组扫描技术在新型农用活性代谢物及其产生菌筛选中的应用黑龙江省博士后基金，作物内生菌中卤化物产生菌的筛选及其活性代谢物的研究东北农业大学博士科研启动金，基因组扫描技术在特殊结构新农药发现中的应用东北农业大学“东农学者—学术骨干”项目，大豆疫霉苏氨酰tRNA合成酶与Borrelidin复合物晶体结构的制备与解析。近五年代表性著作、论文： 近5年，在BioresourceTechnology、MicrobialCellFactories、AppliedMicrobiologyBiotechnoogy和JournalofAgriculturalandFoodChemistry等杂志上发表SCI学术论文30余篇，其中第一作者SCI论文最高影响因子5.039，单篇论文最高它引35次。[1]JiZhang,Xiang-JingWang,Yi-JunYan,etal.Isolationandidentificationof5-hydroxyl-5-methyl-2-hexenoicacidfromActinoplanessp.HBDN08withantifungalactivity.BioresourceTechnology2010,101:8383-8388.(SCI一区，影响因子5.039)[2]JiZhang,Yi-JunYan,JingAn,Sheng-XiongHuang,Xiang-JingWang,Wen-ShengXiang.Designedbiosynthesisof25-methyland25-ethylivermectinwithenhancedinsecticidalactivitybydomainswapofavermectinpolyketidesynthase.MicrobialCellFactories.2015,14:152(SCI一区，影响因子4.22)[3]JiZhang,JingAn,Ji-JiaWang,etal.GeneticengineeringofStreptomycesbingchenggensistoproducemilbemycinsA3/A4asmaincomponentsandeliminatethebiosynthesisofnanchangmycin.ApplMicrobiolBiotechnol2013,97,10091-10101(SCI二区，影响因子3.811)[4]JiZhang,Xiang-JingWang,Yi-JunYan,Wen-ShengXiang.Comparativestudiesontheinteractionofgenistein,8-chlorogenisteinand3',8-dichlorogenisteinwithbovineserumalbumin.JournalofAgriculturalandFoodChemistry2011,59(13):7506-7513(SCI一区，影响因子3.107)[5]JiZhang,XiangjingWang,JinnaoDiao,etal.Streptomycinresistance-aidedgenomeshufflingtoimprovedoramectinproductivityofStreptomycesavermitilisNEAU1069.JournalofIndustrialMicrobiologyandBiotechnology2013,40:877-889(SCI二区，影响因子2.505)[6]MingLi*,JiZhang*,ChongxiLiu,BaozhuFang,WenshengXiang,XiangjingWang.Identificationofborrelidinbindingsiteonthreonyl-tRNAsynthetase.BiochemicalandBiophysicalResearchCommunications2014,451(4):485-490(SCI，影响因子2.281)[7]JiZhang,Ji-DongWang,Chong-XiLiu,etal.AnewprenylatedindolederivativefromendophyticactinobacteriaStreptomycessp.neau-D50.NatProdRes2014,28(7):431-7(SCI，影响因子1.088)[8]TongPan,HairongHe,ChuangLi,JunweiZhao,YuejingZhang,JiansongLi,XiangjingWang,ChongxiLiu,JiZhang(通讯作者),WenshengXiang.Streptomycesdaqingensissp.nov.,isolatedfromsaline-alkalinesoil.IntJSystEvolMicrobiol2016doi:10.1099/ijsem.0.000887(SCI，影响因子2.511)[9]Hai-YanWang,JiZhang,Yue-JingZhang,etal.Combinedapplicationofplasmasmutagensisandgeneengineeringleadsto5-oxomilbemycinsA3/A4asmaincomponentsfromStreptomycesbingchenggensis.AppliedMicrobiologyandBiotechnology.2014,98,9703-9712(SCI二区，影响因子3.811)[10]Xiang-JingWang,JiZhang,Ping-TingQian,etal.ThreenewcyclopentenonederivativesfromActinoalloteichusnanshanensissp.nov.NEAU119.JAsianNatProdRes2014,16:587-592(SCI，影响因子1.130)[11]Xiang-JingWang,JiZhang,Ji-DongWang,etal.NovelcyclopentenonederivativesproducedbyarareactinobacterialstrainActinoalloteichusnanshanensissp.nov.NEAU119.NaturalProductResearch.2013,27(20),1863-1869(SCI，影响因子1.088)[12]GaoYa-mei,WangXiangjing,ZhangJi,etal.Borrelidin,aPotentAntifungalAgent:InsightintotheAntifungalMechanismagainstPhytophthorasojae.JournalofAgriculturalandFoodChemistry2012,60:9874-9881(SCI一区，影响因子3.107)[13]Chong-XiLiu,JiZhang,Xiang-JingWang,etal.AntifungalactivityofborrelidinproducedbyaStreptomycesstrainisolatedfromsoybean.JournalofAgriculturalandFoodChemistry2012,60:1251-1257(SCI一区，影响因子3.107)[14]Xiang-JingWang,JiZhang,Ji-DongWang,etal.FournewdoramectincongenerswithacaricidalandinsecticidalactivityfromStreptomycesavermitilisNEAU1069.ChemistryBiodiversity2011,8,2117-2125(SCI，影响因子1.802)[15]Xiang-JingWang,JiZhang,Chong-XiLiu,etal.AnovelmacrocycliclactonewithbioactivityfromStreptomycesmicroflavusneau3.BioorganicMedicinalChemistryLetters2011,21,5145-5148(SCI，影响因子2.331)