导师姓名：钟莉
性别：
人气指数：74

所属院校：重庆大学
所属院系：生物工程学院
职称：教授
导师类型：博导
招生专业：
研究领域： 再生医学及转化医学，皮肤组织修复-光生物学等。皮肤干细胞的运用；新型生物材料：包括微/纳米... [展开]


研究领域： 再生医学及转化医学，皮肤组织修复-光生物学等。皮肤干细胞的运用；新型生物材料：包括微/纳米生物医学及药物靶向输送治疗肿瘤及其药理机制，功能活性蛋白分子的研究。 [收起]




通讯方式 :
电子邮件：jlzhong@cqu.edu.cn


个人简述 :
2009- 迄今 重庆大学生物工程学院教授；重庆市“百人计划”特聘专家；1981-1997华西医科大学（四川大学）临床医学系本科及四川省人民医院；1997-2008英国巴斯大学药理学系博士；国王学院、UEA、巴斯大学任初级、高级博士后；2008-迄今 兼巴斯大学博士副导师。招收学生 热忱欢迎勤奋好学对跨学科研究有浓厚兴趣生物工程、技术或生物学以及临床医学、化学、化工、物理等背景的学生。重大招生目录071000，083121，083123等。与国内外单位建立了良好合作关系并个性化培养学生。

科研工作 :
主要研究成果：共发表学术论文30余篇。 其中第一及通讯作者文章共15 篇，IF 累计近40分，他引共130余次。1. Zhong JL(钟莉)*, Raval CM, Nisar MF, Zhang J, Tyrrell R. Development of Refractoriness of HO-1 Induction to a Second Treatment with UVA Radiation and the Involvement of Nrf2 in Human Skin Fibroblasts. Photochemistry and photobiology. Nov 201490(6):1340-1348. 2. Nisar MF, Parsons KSG, Bian CX, Julia Li Zhong.* Invited Review：Induction of heme oxygenase-1 in skin fibroblasts by UVA: a potential phototherapeutic strategy of scleroderma. Photobiology and photochemistry. 2015, 91: 210–2203. Huang X, Wang X, Wang S, Yang J, Zhong L, Pan J. UV and dark-triggered repetitive release and encapsulation of benzophenone-3 from biocompatible ZnO nanoparticles potential for skin protection. Nanoscale. 2013 Jun 215(12):5596-601. IF-6.9（JCR 1区)4. Raval CM, Zhong JL, Mitchell SA. Tyrrell RM. The role of Bach1 in ultraviolet a mediated human heme oxygenase 1 regulation in human skin fibroblasts. Free Radic Biol Med. 2012, 52(1):227-36. 5. Aroun A#, Zhong JL# , Tyrrell RM, Pourzand C. Iron, oxidative stress and the example of solar ultraviolet A radiation. Photochem Photobiol Sci., 2012, 11(1):118-134.6. Zhong JL, Yang L, Lü F, Xiao H, Xu R, Wang L, Zhu F, Zhang Y. UVA, UVB and UVC induce differential response signaling pathways converged on the eIF2α phosphorylation. Photochemistry Photobiology, 2011, 87(5): 1092-1104.7. Chiang MY, Yangben Y, Lin NJ, Zhong JL, Yang L. Relationships among cell morphology, intrinsic cell stiffness and cell-substrate interactions. Biomaterials. 2013 34(38):9754-62.8. Xiang Y, Liu G, Yang L, Zhong JL*. UVA-induced protection of skin through the induction of heme oxygenase-1. Review. BioScience Trends. 2011, 5(6):239-244. 9. Tian FF, Zhang FF, Lai XD, Wang LJ, Yang L, Wang X, Singh G, Zhong JL*. Nrf2-mediated protection against UVA radiation in human skin keratinocytes. BioscienceTrend. 2011, 5(1):23-29. 10. Zhong JL, Raval C, Edwards GP, Tyrrell RM. A role of Bach1 and HO-2 in suppression of basal and UVA-induced HO-1 expression in human skin keratinocytes. Free Radic Biol Medicine, 2010, 48(2):196-206.11. Zhong JL, Edwards GP, Raval C, Li H, Tyrrell RM. The Role of Nrf2 in Ultraviolet A Mediated Heme oxygenase 1. Induction in Human Skin Fibroblasts. Photochem. Photobiol Sci, 2010, 9(1):18-24.12. Zhang X#, Zhong JL#, Sun LR, Xun Li X, Ward SG, Shi YQ, Zhang XF, Cheng YN, Gao JJ, Qu X. N(3)-o-toluyl-fluorouracil inhibits human hepatocellular carcinoma cell growth via sustained release of 5-FU. Cancer Chemother Pharmacol. 2010, 66(1):11-19. 13. Sun LR#, Zhong JL#, Cui SX, Li X, Ward SG, Shi YQ, Zhang XF, Cheng YN, Gao JJ, Qu XJ. Modulation of P-glycoprotein activity by substituted quinoxalinones compound QA3 in adriamycin- resistant K562/A02 cells. Pharmacological Reports. 2010, 62(2):333-342.14. Zhong JL, Yiakouvaki A, Holley P, Tyrrell RM, Pourzand C. Susceptibility of skin cells to UVA-induced necrotic cell death reflects the intracellular level of labile iron. J Invest Dermatol. 2004, 123(4):771-780. 15. Moss ML, Powell G, Miller MA, Bin Q, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith L, Lauffenberger D, Petrovich R, Bartsch JW. ADAM9 inhibition increases membrane activity of ADAM10 and controls 2 secretase processing of amyloid precursor protein. J Biol Chem, 2011, 286(47):40443-40451. 16. Li L, Li H, Qian Y, Li X, Singh GK, Zhong L, Liu W, Lv Y, Cai K, Yang L. Electrospun poly (-caprolactone)/silk fibroin core-sheath nanofibers and their potential applications in tissue engineering and drug release. Int J Biological Macromolecules, 2011, 49(2):223-232.17. Li L, Qian Y, Jiang C, Lv Y, Liu W, Zhong L, Cai K, Li S, Yang L. The use of hyaluronan to regulate protein adsorption and cell infiltrationin nanofibrous scaffolds. Biomaterials. 2012, 33(12):3428-3445.