周金培，博士，教授，博士生导师，1965.12出生，药化教研室。1999年药物化学博士研究生毕业后中国药科大学药化教研室从事药物化学的教学与科研工作。2000年获得中国药学会药物化学施维亚奖（Servier）。2001年评为副研究员，2010年评为教授。2005-2006年在日本岐阜药科大学药化室做访问学者。

研究方向：抗肿瘤及心脑血管疾病新药研究。课题研究：已负责完成科技部863博士基金一项；负责完成一项南京市回国人员资助项目。曾参加国家自然科学基金、国家新药基金、“863”项目，医药局局控项目等纵向课题，在国家自然科学基金、新药基金、江苏省自然科学基金等基础研究项目中，依据肿瘤、感染与炎症性疾病、糖尿病等疾病复杂的发病机制和药物的构效关系，进行新药分子设计及合成，以寻找具有自主知识产权的新药。已参与多项基金的评审，为国内外多家SCI杂志论文审稿专家。已申请专利14项，发表论文50余篇。

2003-2006主持国家高技术研究发展计划(863计划)兼有心血管作用的降糖药物设计合成及活性研究，项目编号2003AA2Z3530。

2007-2008主持南京市回国人员基金“具有抗肿瘤活性的1，4取代哌啶类化合物的设计、合成与生物活性研究”

2011-2013参与江苏省产学研联合创新基金前瞻性联合研究项目（BY2011158）

2009-2012参与国家自然科学基金项目“G004抗TXA2受体介导的心血管并发症机制及受体作用模式”项目编号30973638

2009-2012参与国家重大专项“新型降血糖药物G004的研究开发”。项目编号2009ZX09103-094

发表的主要论文：

1.Xueting Cai, Jie Yang , Jinpei Zhou, Wuguang Lu, Chunping Hua, Zhenhua Gu, Jiege Huo ,Xiaoning Wang, Peng Cao. Synthesis and biological evaluation of scopoletin derivatives. Bioorganic & Medicinal Chemistry, 21 (2013), 84-92.
2.Xiong Zhu, Jinpei Zhou*,, Yan Zhu, Xiaowen Hu, Yuemin Bian, Xinting Hu, Zhuo Tao, Cong Gao and Wenlong Huang. Synthesis and Biological Activities of Sulfinyl Acetamide Derivatives for Narcolepsy Treatment.Letters in Drug Design & Discovery, 2013, 10, 266-270
3.Wukun Liu, Jie Hua, Jinpei Zhou*, Huibin Zhang, Haiyang Zhu, Yanhua Cheng, Ronald Gust. Synthesis and in vitro antitumor activity of novel scopoletin derivatives. Bioorganic & Medicinal Chemistry Letters, 22 (2012), 5008-5012
4.Wukun Liu, Jinpei Zhou*, Tong Zhang, Huibin Zhang, Haiyang Zhu, Yanhua Cheng, Ronald Gust. Synthesis and biological evaluation of cyanoguanidine derivatives of loratadine. Bioorganic & Medicinal Chemistry Letters, 22 (2012), 6076-6080.
5.Jinpei Zhou, Lei Wang, Lijuan Wei, Yu Zheng, Huibin Zhang , Yubin Wang, Peng Cao, Ao Niu, Jing Wang and Yue Dai. Synthesis and Antitumor Activity of Scopoletin Derivatives. Letters in Drug Design & Discovery, 2012, 9(4), 397-401
6.Wukun Liu, Jinpei Zhou*, Tong Zhang, Haiyang Zhu, Hai Qian, Huibin Zhang, Wenlong Huang,Ronald Gust. Design and synthesis of thiourea derivatives containing a benzo[5,6]cyclohepta[1,2-b]pyridine moiety as potential antitumor and anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters, 2012, 22: 2701-2704
7.Wukun Liu, Jinpei Zhou#, Yu Zheng, Fan Qi, Huibin Zhang, Hai Qian, Jing Wang1,Yanhua Cheng and Ronald Gust. Design, Synthesis and Antiproliferative Activity of 2-Acetamidothiazole-5-carboxamide Derivatives. Medicinal Chemistry, 2012, 8, 587-594
8. Wukun Liu, Jinpei Zhou*, Fan Qi, Kerstin Bensdorf, Zhiyu Li, Huibin Zhang, Hai Qian,Wenlong Huang, Xueting Cai, Peng Cao, Anja Wellner, and Ronald Gust. Synthesis and Biological Activities of 2-Amino-thiazole-5-carboxylic Acid Phenylamide Derivatives. Arch. Pharm. Chem. Life Sci. 2011, 344, 451–458 451
9. Wukun Liu, Jinpei Zhou*, Kerstin Bensdorf , Huibin Zhang, Haoran Liu, YubinWang , Hai Qian,Yanchun Zhang, Anja Wellner, Gerhard Rubner, Wenlong Huang, Cancheng Guo, Ronald Gust. Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives. European Journal of Medicinal Chemistry, 2011, 46, 907-913
10.Wukun Liu, Jinpei Zhou*, Huibin Zhang, Hai Qian, Jiahan Yin, Kerstin Bensdorf and Ronald Gust. Synthesis and Biological Evaluation of Licofelone Derivatives as Anticancer and Anti-inflammatory Agents. Letters in Drug Design & Discovery, 2011, 8, 911-917
11.Jinpei Zhou, Hai Qian, Huibin Zhang, Hui Gao, Wenlong Huang, Xiaoyun Zhu, Shuaijian Ni, and Chuntao Zhang. Design, Synthesis and Biological Evaluation of Benzopyran Derivatives as KATP Channel Openers. Letters in Drug Design & Discovery, 2010, 7(6), 415-420
12.Jinpei Zhou, Shuaijian Ni, Huibin Zhang, Hai Qian, Yushi Chi, Wenlong Huang, Lu Yu, Xiaowen Hu and Wei Chen. Synthesis and Bioactivity Evaluation of Dipeptidyl Peptidase IV Resistant Glucagon-like Peptide-1 Analogues. Protein and Peptide Letter, 2010, 17(10), 1290-1295
13.Hai Qian, Wei Chen, Xiaoyan Zhang, Huibin Zhang, Jinpei Zhou*, Wenlong Huang, Jing Jin and Dongyan Dai.Synthesis and Biological Evaluation of Dihydroisoquinoline-2(1H)-Carbothioamide Derivatives as TRPV1 Antagonists. Letters in Drug Design & Discovery, 2010, 7(4): 235-237
14.Yanchun Zhang, Jinpei Zhou*, Weihong Pan, Xiaoming Wu, and Shuai Wang.Synthesis and Biological Study of 3-Butyl-1-(2,6-dichlorophenyl)-1H-[1,2,4]triazol-5(4H)-one Derivatives as Anti-hypertension Drugs. Letters in Drug Design & Discovery, 2010, 7(1): 18-22
15.Hai Qian, Wei Chen, Jin Pei Zhou*, Wen Long Huang, Hui Bin Zhang, Jing Jin. Total Synthesis of endothelin 1 by microwave-assisted solid phase method. Chinese Chemical Letters, 2010, 21:388-390
16.Hai Qian, Zhixian Fu, Huibin Zhang, Jinpei Zhou*, Wenlong Huang, Jing Jin, Wei Chen and Dongyan Dai.Synthesis and Biological Evaluation of Capsaicin Derivatives as Analgesia Drugs. Letters in Drug Design & Discovery, 2010, 7(2), 122-127
17.Jinpei Zhou, Xiaowen Hu, Huibin Zhang, Hai Qian, Wenlong Huang, Fan Qi and Yanchun Zhang. Synthesis and Biological Evaluation of 5,6-Dihydro-benzo[c] acridin-7-ol Derivatives as Anti-Alzheimer’s Disease Drugs. Letters in Drug Design & Discovery, 2009，6(8): 623-628
18.Jinpei Zhou, Huibin Zhang, Hai Qian, Liang Lin, Wenlong Huang and Shuaijian Ni. Synthesis and Biological Evaluation of Aromatase Inhibitors. Letters in Drug Design & Discovery, 2009，6(3): 181-185
19.ZHANG Hui-bin, ZHANG Ya-an, WU Guan-zhong, ZHOU Jin-pei*. HUANG Wen-long, HU Xiao-wen. Synthesis and biological evaluation of sulfonylurea and thiourea derivatives substituted with benzenesulfonamide groups as potential hypoglycemic agents. Bioorganic & Medicinal Chemistry Letters, 2009，19（6）：1740-1744
20.Xiangyang Sha, Huibin Zhang, Wenlong Huang, Jinpei Zhou*, Yinghong Zhou. Design and Synthesis of Thiazolidinedione Derivatives as Selective PPARγ Modulators. Letters in Drug Design & Discovery, 2009，6(3): 224-227

申请专利：

1.周金培，魏丽娟，戴岳，张惠斌，蒋企洲.一种制备东莨菪素的新方法.申请号：200910029807.7,公开号：CN101519393A
2.周金培，张惠斌，黄文龙，吴斐华，刘武昆，钱海，程艳华.苯并[5,6]环庚基[1,2-b]吡啶衍生物、制备方法及其药物组合物.申请号：201110153330.0,公开号：CN102260253A
3.周金培，张惠斌，华杰，刘武昆，程艳华.东莨菪素衍生物、制备方法及其用途申请号201210005398.9
4.周金培，张惠斌，华杰，刘武昆，程艳华.3-乙酰氨基-7-羟基-6-甲氧基香豆素衍生物、制备方法及其用途申请号201210005399.3
5.张惠斌，周金培，黄文龙，巫冠中.新的磺酰(硫)脲衍生物、其制备方法及含有它们的药物组合物.专利号：CN1330630C
6.张惠斌,黄文龙,沙向阳,周映红,周金培,钱海,张亚安.取代的四氢异喹啉衍生物、其制备方法及含有它们的药物组合物.申请号：200810155076.6，公开号：CN101386617A

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